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IL17RC Antibody (PACO22750)

SKU:
PACO22750
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€419
Frequently bought together:

Description

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IL17RC Antibody (PACO22750)

The IL17RC Antibody (PAC0270) is a valuable tool for researchers studying the IL17RC protein, a crucial receptor involved in the signaling pathways of interleukin-17 (IL-17). This antibody is produced using high-quality materials and is specifically designed for use in applications such as Western blotting, immunohistochemistry, and flow cytometry.IL17RC plays a key role in immune responses, particularly in the regulation of inflammatory processes. By targeting the IL17RC receptor, researchers can gain insight into the mechanisms underlying various immune-related disorders, including autoimmune diseases and inflammatory conditions.

The IL17RC Antibody (PAC0270) is highly specific for human samples, allowing for accurate detection and analysis in a variety of research settings.Overall, this antibody serves as a valuable tool for scientists looking to further understand the role of IL17RC in immune regulation and inflammation. Its high reactivity and specificity make it an ideal choice for studies focusing on autoimmune diseases, cancer immunotherapy, and other related fields.

Antibody Name:IL17RC Antibody (PACO22750)
Antibody SKU:PACO22750
Size:100ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:Human
Immunogen:Synthesized peptide derived from internal of human IL17RC.
Form:Liquid
Storage Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern blot analysis of extracts from HeLa, HepG2 and HuvEc cells, using IL17RC antibody.
Background:This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.
Synonyms:Interleukin-17 receptor C; IL-17 receptor C; IL-17RC; Interleukin-17 receptor-like protein; IL-17RL
UniProt Protein Function:IL17RC: a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011]Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 3p25.3|3p25.3-p24.1Cellular Component: integral to plasma membraneMolecular Function: interleukin-17 receptor activityBiological Process: cytokine and chemokine mediated signaling pathwayDisease: Candidiasis, Familial, 9
UniProt Protein Details:
NCBI Summary:This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011]
UniProt Code:Q8NAC3
NCBI GenInfo Identifier:229462881
NCBI Gene ID:84818
NCBI Accession:Q8NAC3.2
UniProt Secondary Accession:Q8NAC3,Q6UVY3, Q6UWD4, Q8NFS1, Q9BR97, E9PHG1, E9PHJ6
UniProt Related Accession:Q8NAC3
Molecular Weight:
NCBI Full Name:Interleukin-17 receptor C
NCBI Synonym Full Names:interleukin 17 receptor C
NCBI Official Symbol:IL17RC  
NCBI Official Synonym Symbols:IL17RL; IL17-RL  
NCBI Protein Information:interleukin-17 receptor C; IL-17 receptor C; IL-17RL; IL17F receptor; IL17Rhom; interleukin-17 receptor homolog; interleukin-17 receptor-like protein; zcytoR14
UniProt Protein Name:Interleukin-17 receptor C
UniProt Synonym Protein Names:Interleukin-17 receptor homolog; IL17Rhom; Interleukin-17 receptor-like protein; IL-17RL; ZcytoR14
Protein Family:Interleukin-17 receptor
UniProt Gene Name:IL17RC  
UniProt Entry Name:I17RC_HUMAN
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