IL17RB Rabbit Polyclonal Antibody (CAB10147)
- SKU:
- CAB10147
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | IL17RB Rabbit Polyclonal Antibody |
SKU: | CAB10147 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-292 of human IL17RB (NP_061195.2). |
Sequence: | REPT VQCG SETG PSPE WMLQ HDLI PGDL RDLR VEPV TTSV ATGD YSIL MNVS WVLR ADAS IRLL KATK ICVT GKSN FQSY SCVR CNYT EAFQ TQTR PSGG KWTF SYIG FPVE LNTV YFIG AHNI PNAN MNED GPSM SVNF TSPG CLDH IMKY KKKC VKAG SLWD PNIT ACKK NEET VEVN FTTT PLGN RYMA LIQH STII GFSQ VFEP HQKK QTRA SVVI PVTG DSEG ATVQ LTPY FPTC GSDC IRHK GTVV LCPQ TGVP FPLD NNKS KPGG WLP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:4000 |
Synonyms: | CRL4; EVI27; IL17BR; IL17RH1; IL17RB |
Positive Sample: | HepG2,293T,SW620,A-549,B-cell,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 56kDa |
Observed MW: | 75kDa |
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
Purification Method: | Affinity purification |
Gene ID: | 55540 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |