IL17RA Rabbit Polyclonal Antibody (CAB10052)
- SKU:
- CAB10052
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | IL17RA Rabbit Polyclonal Antibody |
SKU: | CAB10052 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 33-320 of human IL17RA (NP_055154.3). |
Sequence: | LRLL DHRA LVCS QPGL NCTV KNST CLDD SWIH PRNL TPSS PKDL QIQL HFAH TQQG DLFP VAHI EWTL QTDA SILY LEGA ELSV LQLN TNER LCVR FEFL SKLR HHHR RWRF TFSH FVVD PDQE YEVT VHHL PKPI PDGD PNHQ SKNF LVPD CEHA RMKV TTPC MSSG SLWD PNIT VETL EAHQ LRVS FTLW NEST HYQI LLTS FPHM ENHS CFEH MHHI PAPR PEEF HQRS NVTL TLRN LKGC CRHQ VQIQ PFFS SCLN DCLR HSAT VSCP EMPD TPEP IPDY MPLW |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:4000 |
Synonyms: | CD217; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R; IL17RA |
Positive Sample: | HL-60,Mouse liver,Mouse kidney,Mouse lung,Mouse thymus,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 96kDa |
Observed MW: | 100kDa |
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 23765 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |