The IL17B Polyclonal Antibody (PACO07385) is a valuable tool for researchers studying the IL17B cytokine, a member of the Interleukin-17 family known for its role in inflammatory responses and autoimmune diseases. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in various applications, particularly in immunohistochemistry and ELISA.IL17B is involved in the regulation of immune responses and has been implicated in the pathogenesis of several autoimmune conditions, making it a promising target for therapeutic interventions.
By detecting and quantifying IL17B protein expression, researchers can gain insights into its function and potential implications in disease progression. This antibody is ideal for investigations in immunology, rheumatology, and inflammatory disorders, providing a valuable tool for advancing our understanding of IL17B biology and its clinical relevance.
Antibody Name:
IL17B Antibody (PACO07385)
Antibody SKU:
PACO07385
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:10000-1:20000, IHC-p:1:50-1:300
Species Reactivity:
Human, Rat
Immunogen:
Synthetic peptide from human protein at AA range: 1-50
Form:
Liquid
Storage Buffer:
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Purification Method:
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemical analysis of paraffin-embedded human-small-intestine, antibody was diluted at 1:200.
Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.
NCBI Summary:
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015]
