The IL17A Monoclonal Antibody (CAB23226) is a valuable tool for researchers studying IL17A, a pro-inflammatory cytokine involved in immune responses, inflammation, and autoimmune diseases. This monoclonal antibody, developed for use in various research applications, specifically binds to the IL17A protein, allowing for precise detection and analysis in samples.IL17A, also known as Interleukin 17A, is a key player in the immune system's response to infections and plays a critical role in autoimmune disorders such as rheumatoid arthritis and psoriasis. By targeting IL17A, researchers can gain insights into its function and potential therapeutic applications in treating inflammatory conditions.
This monoclonal antibody, produced through advanced technologies, offers high sensitivity and specificity, making it a reliable tool for immunology and disease research. Its compatibility with various techniques, including Western blot and immunohistochemistry, makes it versatile for a wide range of experimental settings. Researchers can trust the IL17A Monoclonal Antibody (CAB23226) for accurate and reliable results in their studies on immune response regulation and inflammatory diseases.
Product Name:
IL17A Monoclonal Antibody
SKU:
CAB23226
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant protein of mouse IL17A.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
Il17; Ctla8; IL-17; Ctla-8; IL-17A; IL17A
Positive Sample:
Recombinant Mouse IL-17 Protein
Conjugate:
Unconjugated
Calculated MW:
17kDa
Observed MW:
17kDa
This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Purification Method:
Affinity purification
Gene ID:
16171
Clone Number:
ARC57567
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of Recombinant Mouse IL-17 Protein, using IL17A Rabbit mAb (CAB23226) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 5ng/1ng per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
