The IL13RA1 Polyclonal Antibody (CAB6628) is specially designed for research involving IL13RA1, a crucial receptor involved in immune response and inflammation regulation. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications.IL13RA1, also known as interleukin 13 receptor alpha 1, plays a significant role in mediating the effects of interleukin-13, which is involved in allergic responses and inflammation. By targeting the IL13RA1 protein, this antibody enables the detection and analysis of IL13RA1 in various cell types, making it an essential tool for studies in immunology, allergy, and inflammatory conditions.
The understanding of IL13RA1 function is essential for developing targeted therapies for diseases where IL13RA1 signaling is dysregulated, such as asthma, allergic disorders, and autoimmune conditions. By using the IL13RA1 Polyclonal Antibody, researchers can explore the role of IL13RA1 in immune modulation and potentially discover new treatment strategies for these diseases.
Product Name:
IL13RA1 Rabbit Polyclonal Antibody
SKU:
CAB6628
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-343 of human IL13RA1 (NP_001551.1).
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Purification Method:
Affinity purification
Gene ID:
3597
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IL13RA1 antibody (CAB6628) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
