The IL12B Polyclonal Antibody is a valuable tool for researchers studying interleukin-12 (IL-12) subunit beta, a cytokine involved in immune response regulation. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it suitable for Western blot applications. By targeting the IL12B protein, this antibody enables researchers to detect and analyze IL-12 beta subunit expression in different cell types, making it ideal for studies in immunology and cancer research.IL-12 is a key player in the immune system, promoting the development of T helper 1 cells and enhancing the cytotoxicity of natural killer cells and cytotoxic T cells.
Dysregulation of IL-12 signaling has been implicated in various diseases, including cancer, autoimmune disorders, and infectious diseases. Therefore, understanding the role of IL-12 subunit beta is crucial for developing targeted therapies that modulate immune responses in these contexts.Overall, the IL12B Polyclonal Antibody offers researchers a reliable tool for investigating the functions of IL-12 subunit beta in immune regulation and disease pathogenesis. Its high specificity and reactivity with human samples make it a valuable asset for studies aiming to unravel the complex mechanisms of the immune system.
Product Name:
IL12B Polyclonal Antibody
SKU:
CAB23054
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant protein of mouse IL12B.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
p40; Il-12b; Il12p40; Il-12p40; IL12B
Positive Sample:
HeLa,U-87 MG,293F
Conjugate:
Unconjugated
Calculated MW:
38kDa
Observed MW:
38kDa
This gene encodes the beta subunit p40 of the Interleukin 12 (IL-12) family of cytokines. Members of the IL-12 family form heterodimers consisting of heavy and light subunits linked by disulfide bonds. The product of this gene, p40, is a subunit of interleukins IL-12 and IL-23.
Purification Method:
Affinity purification
Gene ID:
16160
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using IL12B Rabbit pAb (CAB23054) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
