The IL10 Polyclonal Antibody (CAB21302) is a valuable tool for researchers studying IL10, a cytokine with potent anti-inflammatory properties. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the IL10 protein, it allows for accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in immunology and inflammation.IL10, also known as interleukin-10, is a key regulator of immune responses, playing a critical role in maintaining immune tolerance and preventing excessive inflammation. Dysregulation of IL10 signaling has been linked to various diseases, including autoimmune disorders, inflammatory conditions, and cancer.
By investigating the function of IL10 with the use of this antibody, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets.Overall, the IL10 Polyclonal Antibody (CAB21302) offers researchers a reliable tool for investigating the role of IL10 in immune regulation and disease pathogenesis. Its high specificity and sensitivity make it a valuable asset for advancing our understanding of the complex interplay between cytokines and immune responses.
Product Name:
IL10 Polyclonal Antibody
SKU:
CAB21302
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-178 of rat Rat IL10 (NP_036986.2).
Enables interleukin-10 receptor binding activity. Involved in several processes, including cellular response to estradiol stimulus; liver regeneration; and negative regulation of nitric oxide biosynthetic process. Located in extracellular space. Used to study several diseases, including lung disease (multiple); perinatal necrotizing enterocolitis; sciatic neuropathy; toxic encephalopathy; and transient cerebral ischemia. Biomarker of several diseases, including artery disease (multiple); decubitus ulcer; lung disease (multiple); obstructive sleep apnea; and postpartum depression. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Orthologous to human IL10 (interleukin 10).
Purification Method:
Affinity purification
Gene ID:
25325
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using IL10 Rabbit pAb (CAB21302) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
