IL10 Polyclonal Antibody (CAB20723)
- SKU:
- CAB20723
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
| Product Name: | IL10 Polyclonal Antibody |
| SKU: | CAB20723 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Mouse |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-178 of mouse IL10 (NP_034678.1). |
| Sequence: | SRGQ YSRE DNNC THFP VGQS HMLL ELRT AFSQ VKTF FQTK DQLD NILL TDSL MQDF KGYL GCQA LSEM IQFY LVEV MPQA EKHG PEIK EHLN SLGE KLKT LRMR LRRC HRFL PCEN KSKA VEQV KSDF NKLQ DQGV YKAM NEFD IFIN CIEA YMMI KMKS |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:1000 - 1:5000 |
| Synonyms: | CSIF; If2a; Il-10; IL10 |
| Positive Sample: | Recombinant Mouse IL-10 Protein |
| Conjugate: | Unconjugated |
| Cellular Localization: | extracellular space |
| Calculated MW: | 21kDa |
| Observed MW: | 18kDa/21kDa |
This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis.
| Purification Method: | Affinity purification |
| Gene ID: | 16153 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates, using IL10 Rabbit pAb (CAB20723) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s. |
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