The IL10 Polyclonal Antibody (CAB20723) is a valuable tool for researchers studying interleukin-10 (IL-10), a key anti-inflammatory cytokine involved in immune regulation. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blot applications. By targeting the IL-10 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it highly suitable for research in immunology and inflammatory diseases.IL-10 is known for its potent anti-inflammatory effects, playing a crucial role in immune tolerance and immune response regulation.
Dysregulation of IL-10 has been implicated in various inflammatory conditions, autoimmune diseases, and cancer progression. Therefore, studying the function and expression of IL-10 is essential for gaining insights into disease mechanisms and developing targeted therapies.Overall, the IL10 Polyclonal Antibody (CAB20723) provides researchers with a reliable tool for investigating the role of IL-10 in health and disease, offering valuable insights into potential therapeutic interventions for inflammatory disorders and autoimmune conditions.
Product Name:
IL10 Polyclonal Antibody
SKU:
CAB20723
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-178 of mouse IL10 (NP_034678.1).
This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis.
Purification Method:
Affinity purification
Gene ID:
16153
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using IL10 Rabbit pAb (CAB20723) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
