The IL-1RA Monoclonal Antibody is a specialized antibody designed for research involving IL-1RA, a key cytokine mediator involved in the regulation of inflammation and immune responses. This antibody, developed using advanced monoclonal antibody technology, specifically targets IL-1RA, allowing for precise detection and analysis in various experimental settings.IL-1RA, also known as Interleukin-1 receptor antagonist, serves as a natural inhibitor of the pro-inflammatory effects of IL-1α and IL-1β. By binding to IL-1 receptors and preventing their activation, IL-1RA plays a crucial role in maintaining immune balance and preventing excessive inflammation. Research into IL-1RA function is essential for understanding its role in inflammatory diseases, autoimmune disorders, and other conditions characterized by dysregulated immune responses.
The IL-1RA Monoclonal Antibody offers researchers a powerful tool for investigating the role of IL-1RA in various biological processes and disease states. Its high specificity and sensitivity enable accurate detection of IL-1RA in experimental samples, providing valuable insights into its function and potential therapeutic applications. Whether studying inflammatory pathways, immune regulation, or cytokine signaling, this antibody is an invaluable resource for advancing scientific understanding in immunology and related fields.
Product Name:
IL-1RA Monoclonal Antibody
SKU:
CAB23956
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-178 of mouse IL-1RA ( NP_001034790.1).
Predicted to enable cytokine receptor binding activity. Acts upstream of or within insulin secretion and lipid metabolic process. Located in extracellular region and vesicle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); kidney failure (multiple); lung disease (multiple); and vascular disease (multiple). Orthologous to human IL1RN (interleukin 1 receptor antagonist).
Purification Method:
Affinity purification
Gene ID:
16181
Clone Number:
ARC62499
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using IL-1RA Rabbit mAb (CAB23956) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
