The IL-17A Receptor Rabbit Monoclonal Antibody (CAB5163) is a valuable tool for researchers studying the IL-17A receptor, a key player in inflammation and immune responses. This antibody, generated in rabbits, is highly specific for the IL-17A receptor and has been validated for use in various applications including Western blotting.The IL-17A receptor is known to be involved in various inflammatory conditions and autoimmune diseases, making it a promising target for therapeutic interventions. By using this antibody, researchers can effectively detect and analyze the IL-17A receptor in different cell types, providing valuable insights into its role in disease pathogenesis.
With its high reactivity and specificity, the IL-17A Receptor Rabbit Monoclonal Antibody (CAB5163) is an essential tool for scientists conducting research in immunology, inflammation, and autoimmune disorders. Its ability to target the IL-17A receptor opens up new possibilities for understanding and potentially treating a range of debilitating conditions.
Product Name:
IL17RA Rabbit Monoclonal Antibody
SKU:
CAB5163
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 767-866 of human IL17RA (Q96F46).
Membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
96kDa
Observed MW:
120kDa
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
23765
Clone Number:
ARC1240
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IL17RA Rabbit mAb (CAB5163) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
