IL17RA Rabbit Monoclonal Antibody (CAB5163)
- SKU:
- CAB5163
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | IL17RA Rabbit Monoclonal Antibody |
SKU: | CAB5163 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 767-866 of human IL17RA (Q96F46). |
Sequence: | GCSR PAMV LTDP HTPY EEEQ RQSV QSDQ GYIS RSSP QPPE GLTE MEEE EEEE QDPG KPAL PLSP EDLE SLRS LQRQ LLFR QLQK NSGW DTMG SESE GPSA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CD217; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R; IL17RA |
Positive Sample: | Mouse lung,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 96kDa |
Observed MW: | 120kDa |
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 23765 |
Clone Number: | ARC1240 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |