IL 12p40 Monoclonal Antibody [NYRmIL-12p40] (CPAB0348)
- SKU:
- CPAB0348
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- IgG2a
- Clone:
- NYRmIL-12p40
- Applications:
- IP
- WB
- ELISA
Description
IL 12p40 Monoclonal Antibody [NYRmIL-12p40] (CPAB0348)
The IL-12p40 Polyclonal Antibody (CPAB0348) is a valuable tool for researchers studying the IL-12p40 protein, which is a subunit of the cytokine IL-12. This antibody, raised in rabbits, is highly specific and reactive with human, mouse, and rat samples, making it versatile for a wide range of research applications.IL-12p40 plays a crucial role in immune regulation, particularly in the development of Th1 cells and the promotion of cell-mediated immunity. It is involved in the regulation of inflammatory responses and has been implicated in various diseases, including infections, autoimmune disorders, and cancer.
This antibody is validated for use in Western blot and immunohistochemistry applications, allowing for the detection and analysis of IL-12p40 expression in different cell types and tissues. Its high specificity and reactivity make it a reliable tool for researchers investigating the role of IL-12p40 in immunology, oncology, and inflammatory diseases.
Product Name: | IL 12p40 Antibody |
Product Sku: | CPAB0348 |
Size: | 500μg |
Host Species: | Rat |
Immunogen: | r.Murine IL-12 p4 |
Clone: | NYRmIL-12p40. |
Reactivity: | Mouse |
Applications: | Immuneprecipitation, Western Blot, ELISA |
Purification Method: | Ion exchange |
Isotype: | IgG2a |
Background: | Active IL-12 is a p70 disulphide-linked dimer composed of p35 and p40 subunits. The protein is a pleiotropic cytokine produced primarily by antigen presenting cells and has multiple effects on T lymphocytes and natural killer cells in terms of stimulating cytotoxicity, proliferation, production of other cytokines and Th1 subset differentiation. |
Synonyms: | NKSF2, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40), TSF, Edodekin-alpha, IL-12 p40, IL-12B, IL-12 subunit p40, NK cell stimulatory factor chain 2. |
Storage Buffer: | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |