Description
IL 1 Beta Monoclonal Antibody [NYR-hIL1b] (CPAB0054)
The IL-1 Beta Polyclonal Antibody (CPAB0054) is a powerful tool for researchers studying the cytokine interleukin-1 beta (IL-1β), a key player in the inflammatory response. This antibody, raised in rabbits, shows high reactivity with human samples and has been validated for use in Western blot and other applications.IL-1β is a potent pro-inflammatory cytokine that plays a crucial role in the immune system's response to infection and injury. Dysregulation of IL-1β signaling has been implicated in a variety of diseases, including autoimmune disorders, inflammatory conditions, and cancer.
By targeting IL-1β, researchers hope to uncover new therapeutic strategies for these challenging conditions.The IL-1 Beta Polyclonal Antibody enables precise detection and analysis of IL-1β protein levels in various cell types, providing valuable insights into its role in health and disease. Its versatility and reliability make it an essential tool for immunology and cancer research, as well as drug development efforts aimed at modulating the inflammatory response.
Product Name: | IL 1 Beta Antibody |
Product Sku: | CPAB0054 |
Size: | 500μg |
Host Species: | Mouse |
Immunogen: | r.Human IL-1b |
Clone: | NYR-hIL1b. |
Reactivity: | Human |
Applications: | Immuneprecipitation, Western Blot, ELISA, Immunohistochemistry |
Purification Method: | Ion exchange |
Isotype: | IgG2b |
Background: | Interleukin-1b is produced by activated macrophages, IL-1B stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. IL1B proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
Synonyms: | Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF), IL1F2, IL-1 beta. |
Storage Buffer: | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |