IKZF3 Rabbit Polyclonal Antibody (CAB7287)
- SKU:
- CAB7287
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | IKZF3 Rabbit Polyclonal Antibody |
SKU: | CAB7287 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 280-450 of human IKZF3 (NP_036613.2). |
Sequence: | HCFD VNYN SSYM YEKE SELI QTRM MDQA INNA ISYL GAEA LRPL VQTP PAPT SEMV PVIS SMYP IALT RAEM SNGA PQEL EKKS IHLP EKSV PSER GLSP NNSG HDST DTDS NHEE RQNH IYQQ NHMV LSRA RNGM PLLK EVPR SYEL LKPP PICP RDSV KVIN KEGE VMD |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | AIO; IMD84; AIOLOS; ZNFN1A3; IKZF3 |
Positive Sample: | BT-474,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 58kDa |
Observed MW: | 58kDa |
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
Purification Method: | Affinity purification |
Gene ID: | 22806 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |