The IKZF2 Polyclonal Antibody (CAB12265) is a valuable tool for researchers studying IKZF2, a key transcription factor involved in immune cell development and function. This antibody, generated in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blotting applications. By targeting the IKZF2 protein, this antibody allows for the detection and analysis of IKZF2 expression in a variety of cell types, making it an essential reagent for studies in immunology and cancer research.IKZF2, also known as Helios, plays a crucial role in the regulation of immune responses, particularly in the differentiation and function of T cells.
Its involvement in immune cell development and maintenance makes it a promising target for exploring the pathogenesis of autoimmune diseases, leukemia, and other immune-related disorders. Investigating the function of IKZF2 with the help of this antibody could provide insights into the mechanisms underlying these conditions and aid in the development of targeted therapies.
Product Name:
IKZF2 Rabbit Polyclonal Antibody
SKU:
CAB12265
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-440 of human IKZF2 (NP_001072994.1).
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.
Purification Method:
Affinity purification
Gene ID:
22807
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IKZF2 Rabbit pAb (CAB12265) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
