The IKKbeta Rabbit Monoclonal Antibody (CAB19606) is a valuable tool for researchers studying IKKbeta, a key regulator of the NF-kappaB signaling pathway involved in inflammation, immunity, and cell survival. This antibody, generated in rabbits, exhibits high specificity and sensitivity for human samples and has been validated for use in Western blotting and immunohistochemistry applications.IKKbeta serves as a crucial mediator in the activation of NF-kappaB, a transcription factor that plays a central role in regulating various cellular processes, including immune responses and cell proliferation. Dysregulation of the NF-kappaB pathway is associated with a variety of diseases, such as cancer, autoimmune disorders, and inflammatory conditions.
By targeting IKKbeta, researchers can gain insights into the underlying mechanisms of these diseases and develop potential therapeutic strategies.The IKKbeta Rabbit Monoclonal Antibody (CAB19606) provides a reliable tool for analyzing IKKbeta expression and activity in different biological samples, allowing for a better understanding of its functions in various physiological and pathological contexts. Its versatility and specificity make it an indispensable resource for investigations in immunology, oncology, and other areas of biomedical research.
Product Name:
IKKβ Rabbit Monoclonal Antibody
SKU:
CAB19606
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 450-756 of human IKKβ (O14920).
The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3551
Clone Number:
ARC2632
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Confocal imaging of HeLa cells using IKKβ Rabbit mAb (A19606,dilution 1:100)(Red). The cells were counterstained with α-Tubulin Mouse mAb (AC012,dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 100x.
