The IKKalpha Rabbit Monoclonal Antibody (CAB19694) is a valuable tool for researchers studying IKKalpha, a key regulator of the NF-kappaB signaling pathway essential for inflammation and immune responses. This antibody, produced using rabbit monoclonal technology, exhibits high specificity and sensitivity in detecting IKKalpha in human samples, making it ideal for use in Western blot and immunohistochemistry applications.IKKalpha, also known as Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Alpha, plays a crucial role in regulating the expression of genes involved in inflammation, immunity, and cell survival. Dysregulation of IKKalpha activity has been implicated in various diseases, including cancer, inflammatory disorders, and autoimmune conditions.
By targeting IKKalpha, researchers can gain valuable insights into the molecular mechanisms underlying these diseases and potentially develop new therapeutic strategies.The IKKalpha Rabbit Monoclonal Antibody (CAB19694) offers researchers a reliable tool for investigating the function and expression of IKKalpha in different cellular contexts, providing valuable information for advancing our understanding of inflammatory processes and immune responses. Its high specificity and sensitivity make it a trusted reagent for immunology, oncology, and inflammation research.
Product Name:
IKKα Rabbit Monoclonal Antibody
SKU:
CAB19694
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IKKα (NP_001269.3).
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Purification Method:
Affinity purification
Gene ID:
1147
Clone Number:
ARC0174
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IKKα antibody (CAB19694) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
