IKKα Polyclonal Antibody (CAB21354)
- SKU:
- CAB21354
Frequently bought together:
Description
| Product Name: | IKKα Polyclonal Antibody |
| SKU: | CAB21354 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600-700 of human IKKα (NP_001269.3). |
| Sequence: | VLKE LFGH LSKL LGCK QKII DLLP KVEV ALSN IKEA DNTV MFMQ GKRQ KEIW HLLK IACT QSSA RSLV GSSL EGAV TPQT SAWL PPTS AEHD HSLS CVVT P |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:500 - 1:2000 |
| Synonyms: | BPS2; IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha; IKKα |
| Positive Sample: | Jurkat,HeLa |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cytoplasm, Nucleus. |
| Calculated MW: | 85kDa |
| Observed MW: | 94kDa/85kDa |
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
| Purification Method: | Affinity purification |
| Gene ID: | 1147 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
 | Western blot analysis of lysates from Jurkat cells using [KO Validated] IKKα Rabbit pAb(CAB21354) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s. |
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