IKKε Rabbit Polyclonal Antibody (CAB16470)
- SKU:
- CAB16470
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | IKKε Rabbit Polyclonal Antibody |
SKU: | CAB16470 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 460-620 of human IKKε (NP_001180251.1). |
Sequence: | VART SLLY LSSS LGTE RFSS VAGT PEIQ ELKA AAEL RSRL RTLA EVLS RCSQ NITE TQES LSSL NREL VKSR DQVH EDRS IQQI QCCL DKMN FIYK QFKK SRMR PGLG YNEE QIHK LDKV NFSH LAKR LLQV FQEE CVQK YQAS LVTH GKRM RVVH ETRN H |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | IKKE; IKKI; IKK-E; IKK-i; IKKε |
Positive Sample: | K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, PML body. |
Calculated MW: | 80kDa |
Observed MW: | 110kDa |
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).
Purification Method: | Affinity purification |
Gene ID: | 9641 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |