IKKε Rabbit Polyclonal Antibody (CAB14093)
- SKU:
- CAB14093
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | IKKε Rabbit Polyclonal Antibody |
SKU: | CAB14093 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 495-716 of human IKKε (NP_054721.1). |
Sequence: | LRSR LRTL AEVL SRCS QNIT ETQE SLSS LNRE LVKS RDQV HEDR SIQQ IQCC LDKM NFIY KQFK KSRM RPGL GYNE EQIH KLDK VNFS HLAK RLLQ VFQE ECVQ KYQA SLVT HGKR MRVV HETR NHLR LVGC SVAA CNTE AQGV QESL SKLL EELS HQLL QDRA KGAQ ASPP PIAP YPSP TRKD LLLH MQEL CEGM KLLA SDLL DNNR IIER LNRV PAPP DV |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | IKKE; IKKI; IKK-E; IKK-i; IKKε |
Positive Sample: | K-562,293T,SW480,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, PML body. |
Calculated MW: | 80kDa |
Observed MW: | 80kDa |
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).
Purification Method: | Affinity purification |
Gene ID: | 9641 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |