The IKBKB Polyclonal Antibody (CAB2087) is a valuable tool for researchers studying IKBKB, a key protein involved in the regulation of immune and inflammatory responses. This antibody, produced through immunization of rabbits, exhibits high reactivity with human samples and is suitable for Western blot applications. By specifically binding to the IKBKB protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in immunology and cancer research.IKBKB, also known as inhibitor of nuclear factor kappa-B kinase subunit beta, plays a crucial role in the activation of the NF-kappa-B signaling pathway, which is involved in various cellular processes such as inflammation, immune responses, and cell survival.
Dysregulation of this pathway has been implicated in a range of diseases, including cancer, autoimmune disorders, and inflammatory conditions. Therefore, understanding the function of IKBKB is essential for developing targeted therapies that modulate immune responses in the context of these diseases.Overall, the IKBKB Polyclonal Antibody (CAB2087) is a reliable tool for researchers seeking to explore the role of IKBKB in immune regulation and inflammatory pathways, offering valuable insights into the mechanisms driving various diseases and potential targets for therapeutic intervention.
Product Name:
IKKβ Rabbit Polyclonal Antibody
SKU:
CAB2087
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-669 of human IKKβ (NP_001547.1).
The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3551
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of NIH/3T3 cells using IKKβ Rabbit pAb (CAB2087) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
