IKBKAP Rabbit Polyclonal Antibody (CAB10127)
- SKU:
- CAB10127
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | IKBKAP Rabbit Polyclonal Antibody |
SKU: | CAB10127 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1093-1332 of human IKBKAP (NP_003631.2). |
Sequence: | LRLV YKYN RLDI IETN VKPS ILEA QKNY MAFL DSQT ATFS RHKK RLLV VREL KEQA QQAG LDDE VPHG QESD LFSE TSSV VSGS EMSG KYSH SNSR ISAR SSKN RRKA ERKK HSLK EGSP LEDL ALLE ALSE VVQN TENL KDEV YHIL KVLF LFEF DEQG RELQ KAFE DTLQ LMER SLPE IWTL TYQQ NSAT PVLG PNST ANSI MASY QQQK TSVP VLDA ELFI PPKI NRRT QWKL SLLD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:4000 IHC-P,1:50 - 1:200 |
Synonyms: | FD; DYS; IKAP; IKI3; TOT1; IKBKAP |
Positive Sample: | HeLa,HepG2,U-251MG,HL-60,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 150kDa |
Observed MW: | 150kDa |
The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 8518 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |