IκBα Rabbit Polyclonal Antibody (CAB16929)
- SKU:
- CAB16929
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | IκBα Rabbit Polyclonal Antibody |
SKU: | CAB16929 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 166-265 of human IκBα (NP_065390.1). |
Sequence: | SCTT PHLH SILK ATNY NGHT CLHL ASIH GYLG IVEL LVSL GADV NAQE PCNG RTAL HLAV DLQN PDLV SLLL KCGA DVNR VTYQ GYSP YQLT WGRP STRI |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | IKBA; MAD-3; NFKBI; EDAID2; IκBα |
Positive Sample: | MCF7,NIH/3T3,Mouse thymus,Rat liver |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 36kDa |
Observed MW: | 36kDa |
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Purification Method: | Affinity purification |
Gene ID: | 4792 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |