The IGSF8 Polyclonal Antibody (CAB14297) is specially designed for research involving IGSF8, a cell surface protein implicated in various cellular functions. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the IGSF8 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it a valuable tool for studies in immunology and cancer research.IGSF8, also known as Immunoglobulin superfamily member 8, plays a crucial role in cell adhesion and communication, making it an attractive target for investigations into cell signaling pathways and interactions.
Its involvement in various physiological processes suggests its potential significance in disease pathogenesis, particularly in conditions such as cancer and autoimmune disorders. Research on IGSF8 could provide valuable insights into the mechanisms underlying these diseases and aid in the development of targeted therapeutic strategies.Overall, the IGSF8 Polyclonal Antibody (CAB14297) offers researchers a reliable tool for studying the function and expression of IGSF8 in different cellular contexts, paving the way for advancements in our understanding of its role in health and disease.
Product Name:
IGSF8 Rabbit Polyclonal Antibody
SKU:
CAB14297
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-350 of human IGSF8 (NP_443100.1).
This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.
Purification Method:
Affinity purification
Gene ID:
93185
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Raji cells, using IGSF8 Rabbit pAb (CAB14297) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
