The IGLL5 Antibody (PAC035054) is a polyclonal antibody developed for research involving IGLL5, a key protein involved in B-cell development and function. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it an excellent tool for use in Western blot and immunohistochemistry applications. IGLL5, also known as immunoglobulin lambda-like polypeptide 5, plays a crucial role in the differentiation and maturation of B-cells, which are essential components of the immune system. By targeting IGLL5, researchers can gain insights into the functions of B-cells in immune responses, as well as in diseases such as leukemia and lymphoma where B-cell abnormalities are present.
Studying IGLL5 with this antibody can provide valuable information for understanding the mechanisms underlying B-cell development and function, as well as potential therapeutic strategies for targeting B-cell related diseases. Its high specificity and reactivity with human samples make it a reliable tool for researchers in immunology, oncology, and beyond.
Antibody Name:
IGLL5 Antibody (PACO35054)
Antibody SKU:
PACO35054
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Immunoglobulin lambda-like polypeptide 5 protein (36-214AA)
IGLL5: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 22q11.22Cellular Component: external side of plasma membraneMolecular Function: antigen bindingBiological Process: B cell receptor signaling pathway; complement activation, classical pathway; defense response to bacterium; innate immune response; phagocytosis, engulfment; phagocytosis, recognition; positive regulation of B cell activation
UniProt Protein Details:
NCBI Summary:
This gene encodes one of the immunoglobulin lambda-like polypeptides. It is located within the immunoglobulin lambda locus but it does not require somatic rearrangement for expression. The first exon of this gene is unrelated to immunoglobulin variable genes; the second and third exons are the immunoglobulin lambda joining 1 and the immunoglobulin lambda constant 1 gene segments. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
