The IGHMBP2 Polyclonal Antibody (CAB7240) is a valuable tool for researchers studying IGHMBP2, a protein involved in RNA processing and mitochondrial function. This antibody, produced in rabbits, is specifically designed for use in Western blot applications and has been validated for its reactivity with human samples. By binding to the IGHMBP2 protein, this antibody enables the detection and analysis of IGHMBP2 in various cell types, making it an ideal choice for studies in molecular biology and mitochondrial research.IGHMBP2 is known to play a crucial role in maintaining mitochondrial stability and ensuring proper RNA metabolism, making it a key player in cellular homeostasis.
Dysregulation of IGHMBP2 has been linked to various neurological disorders and mitochondrial dysfunction, highlighting the importance of understanding its mechanisms of action. The IGHMBP2 Polyclonal Antibody provides researchers with a reliable tool for investigating the function and expression of IGHMBP2 in both normal and disease states, facilitating advancements in the fields of neurobiology and mitochondrial research.
Enables G-rich single-stranded DNA binding activity and ribosome binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II; neuromuscular process; and spinal cord motor neuron differentiation. Located in several cellular components, including growth cone; neuronal cell body; and perinuclear region of cytoplasm. Part of ribonucleoprotein complex. Is expressed in several structures, including genitourinary system; heart; liver; lung; and nervous system. Used to study distal spinal muscular atrophy 1. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2S and distal spinal muscular atrophy 1. Orthologous to human IGHMBP2 (immunoglobulin mu DNA binding protein 2).
Purification Method:
Affinity purification
Gene ID:
20589
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IGHMBP2 antibody (CAB7240) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
