Human IgG1/Immunoglobulin heavy constant gamma 1 Polyclonal Antibody (CAB24654)
- SKU:
- CAB24654
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | Human IgG1/Immunoglobulin heavy constant gamma 1 Polyclonal Antibody |
SKU: | CAB24654 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-130 of human IgG1/Immunoglobulin heavy constant gamma 1(P01857). |
Sequence: | GTAA LGCL VKDY FPEP VTVS WNSG ALTS GVHT FPAV LQSS GLYS LSSV VTVP SSSL GTQT YICN VNHK PSNT KVDK KVEP KSCD KTHT CPPC PAPE LLGG PSVF LFPP KP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Positive Sample: | Human plasma,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cell Membrane and Secreted |
Calculated MW: | 44kDa |
Observed MW: | 55kDa/35kDa |
IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).
Purification Method: | Affinity purification |
Gene ID: | 3500 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |