The IGFL3 Polyclonal Antibody (CAB7154) is a valuable tool for researchers studying IGFL3, a member of the insulin-like growth factor (IGF) family that plays a role in cellular growth and development. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the IGFL3 protein, researchers can detect and analyze its expression in various cell types, making it an ideal tool for investigations in developmental biology and cancer research.
IGFL3, also known as insulin-like growth factor-binding protein 11 (IGFBP11), is involved in the regulation of IGF signaling, which is crucial for cell proliferation and differentiation. Understanding the function of IGFL3 can provide insights into its potential role in disease processes, such as cancer and metabolic disorders. By elucidating the mechanisms by which IGFL3 affects cellular growth and metabolism, researchers can potentially uncover new therapeutic targets for various conditions.
Product Name:
IGFL3 Rabbit Polyclonal Antibody
SKU:
CAB7154
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-125 of human IGFL3 (NP_997276.1).
IGFL3 belongs to the insulin-like growth factor (IGF; see MIM 147440) family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth (Emtage et al., 2006 [PubMed 16890402]).
Purification Method:
Affinity purification
Gene ID:
388555
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse liver, using IGFL3 antibody (CAB7154) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
