The IGFBP7 Rabbit Monoclonal Antibody (CAB4615) is a valuable tool for researchers studying Insulin-like Growth Factor Binding Protein 7 (IGFBP7), a protein known to play a role in various biological processes such as cell growth, differentiation, and apoptosis. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity for detecting IGFBP7 in human samples.IGFBP7 is involved in regulating cell proliferation and survival, making it a potential target for cancer research and therapeutic development. By targeting IGFBP7, researchers can gain insights into its function in promoting or inhibiting tumor growth, providing valuable information for the development of targeted cancer therapies.
This antibody is validated for use in Western blot applications, enabling researchers to detect IGFBP7 with high accuracy and reproducibility. Its versatility in detecting IGFBP7 in various cell types makes it an ideal tool for studying the role of IGFBP7 in both normal physiological processes and disease states, such as cancer progression.Overall, the IGFBP7 Rabbit Monoclonal Antibody (CAB4615) offers researchers a reliable and efficient tool for investigating the role of IGFBP7 in cancer biology and other related fields, ultimately advancing our understanding of this important protein and its potential implications for therapeutic interventions.
Product Name:
IGFBP7 Rabbit Monoclonal Antibody
SKU:
CAB4615
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IGFBP7 (Q16270).
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).
Purification Method:
Affinity purification
Gene ID:
3490
Clone Number:
ARC1052
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IGFBP7 Rabbit mAb (CAB4615) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
