IGFBP7 Rabbit Polyclonal Antibody (CAB13023)
- SKU:
- CAB13023
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | IGFBP7 Rabbit Polyclonal Antibody |
SKU: | CAB13023 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-282 of human IGFBP7 (NP_001544.1). |
Sequence: | SSSD TCGP CEPA SCPP LPPL GCLL GETR DACG CCPM CARG EGEP CGGG GAGR GYCA PGME CVKS RKRR KGKA GAAA GGPG VSGV CVCK SRYP VCGS DGTT YPSG CQLR AASQ RAES RGEK AITQ VSKG TCEQ GPSI VTPP KDIW NVTG AQVY LSCE VIGI PTPV LIWN KVKR GHYG VQRT ELLP GDRD NLAI QTRG GPEK HEVT GWVL VSPL SKED AGEY ECHA SNSQ GQAS ASAK ITVV DALH EIPV KKGE GAEL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1; IGFBP7 |
Positive Sample: | Mouse kidney,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 29kDa |
Observed MW: | 35kDa |
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).
Purification Method: | Affinity purification |
Gene ID: | 3490 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |