The IGFBP5 Polyclonal Antibody (CAB1720) is an essential tool for researchers studying insulin-like growth factor binding protein 5 (IGFBP5), a key player in cell growth and survival. This antibody, produced in rabbits, is highly specific and reactive to human samples, making it ideal for use in Western blot applications. By binding to the IGFBP5 protein, this antibody enables the detection and analysis of IGFBP5 levels in various cell types.IGFBP5 is a vital regulator of cell proliferation, differentiation, and apoptosis, making it a target of interest in cancer research and developmental biology.
Its role in modulating insulin-like growth factor signaling pathways highlights its potential as a therapeutic target in diseases like cancer and metabolic disorders. By studying the function of IGFBP5, researchers can uncover new insights into cell growth mechanisms and potentially develop novel treatments for various diseases.
Product Name:
IGFBP5 Rabbit Polyclonal Antibody
SKU:
CAB1720
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 68-167 of human IGFBP5 (NP_000590.1).
Enables insulin-like growth factor I binding activity. Involved in several processes, including cellular response to cAMP; regulation of smooth muscle cell migration; and regulation of smooth muscle cell proliferation. Part of insulin-like growth factor ternary complex. Biomarker of pulmonary fibrosis.
Purification Method:
Affinity purification
Gene ID:
3488
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IGFBP5 Rabbit pAb (CAB1720) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
