The IGFBP5 Polyclonal Antibody (CAB13858) is a valuable tool for researchers studying insulin-like growth factor binding protein 5 (IGFBP5), a key player in regulating cell growth and differentiation. This antibody, raised in rabbits, shows high reactivity with human samples and has been validated for use in various applications, including Western blotting.IGFBP5 is involved in modulating the activity of insulin-like growth factors (IGFs), which play a crucial role in cell proliferation, survival, and metabolism. Dysregulation of IGFBP5 has been implicated in various diseases, including cancer, cardiovascular disorders, and metabolic syndrome.
By targeting IGFBP5, researchers may uncover new insights into these conditions and potentially identify novel therapeutic targets.The IGFBP5 Polyclonal Antibody enables the detection and analysis of IGFBP5 protein levels in various cell types, making it an invaluable tool for studies in molecular biology, cancer research, and endocrinology. By further understanding the role of IGFBP5 in cellular processes, researchers can advance our knowledge of disease mechanisms and potentially develop innovative treatments for related disorders.
Product Name:
IGFBP5 Rabbit Polyclonal Antibody
SKU:
CAB13858
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-272 of human IGFBP5 (NP_000590.1).
Enables insulin-like growth factor I binding activity. Involved in several processes, including cellular response to cAMP; regulation of smooth muscle cell migration; and regulation of smooth muscle cell proliferation. Part of insulin-like growth factor ternary complex. Biomarker of pulmonary fibrosis.
Purification Method:
Affinity purification
Gene ID:
3488
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of 293T, using IGFBP5 Rabbit pAb (CAB13858) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
