The IGFBP2 Polyclonal Antibody (CAB0403) is a valuable tool for research involving the Insulin-like Growth Factor Binding Protein 2 (IGFBP2). IGFBP2 is a member of the IGFBP family, known for its role in regulating the activity of insulin-like growth factors. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.IGFBP2 is involved in various biological processes, including cell growth, differentiation, and metabolism. Its dysregulation has been linked to several diseases, such as cancer, diabetes, and cardiovascular disorders, making it a key target for research in these areas.
By using the IGFBP2 Polyclonal Antibody, researchers can accurately detect and analyze the expression of IGFBP2 in different cell types, aiding in the study of its function and potential therapeutic applications.Overall, the IGFBP2 Polyclonal Antibody is a reliable tool for investigating the role of IGFBP2 in health and disease, providing valuable insights that can contribute to the development of new treatments and strategies for improving human health.
Product Name:
IGFBP2 Rabbit Polyclonal Antibody
SKU:
CAB0403
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human IGFBP2 (NP_000588.2).
The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3485
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IGFBP2 antibody (CAB0403) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
