IGF2BP3 Rabbit Polyclonal Antibody (CAB6099)
- SKU:
- CAB6099
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | IGF2BP3 Rabbit Polyclonal Antibody |
SKU: | CAB6099 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-579 of human IGF2BP3 (NP_006538.2). |
Sequence: | KKIE QDTD TKIT ISPL QELT LYNP ERTI TVKG NVET CAKA EEEI MKKI RESY ENDI ASMN LQAH LIPG LNLN ALGL FPPT SGMP PPTS GPPS AMTP PYPQ FEQS ETET VHLF IPAL SVGA IIGK QGQH IKQL SRFA GASI KIAP AEAP DAKV RMVI ITGP PEAQ FKAQ GRIY GKIK EENF VSPK EEVK LEAH IRVP SFAA GRVI GKGG KTVN ELQN LSSA EVVV PRDQ TPDE NDQV VVKI TGHF YACQ VAQR KIQE ILTQ VKQH QQQK ALQS GPPQ SRRK |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3; IGF2BP3 |
Positive Sample: | HeLa,T-47D,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 64kDa |
Observed MW: | 64kDa |
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
Purification Method: | Affinity purification |
Gene ID: | 10643 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |