The IGF2BP2 Polyclonal Antibody (CAB2749) is a valuable tool for researchers studying IGF2BP2, a key protein involved in post-transcriptional regulation of gene expression. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By binding specifically to the IGF2BP2 protein, researchers can accurately detect and analyze its expression in a variety of cell types.IGF2BP2, also known as insulin-like growth factor 2 mRNA-binding protein 2, plays a crucial role in the regulation of mRNA stability and translation, impacting various cellular processes such as proliferation, differentiation, and apoptosis.
Dysregulation of IGF2BP2 has been implicated in diseases like cancer, diabetes, and neurological disorders, making it a promising target for therapeutic intervention.By studying the expression and function of IGF2BP2 using this polyclonal antibody, researchers can gain valuable insights into its role in disease pathology and potentially uncover new targets for drug development. This antibody is a valuable resource for scientists working in the fields of molecular biology, oncology, and metabolism research.
Product Name:
IGF2BP2/IMP2 Rabbit Polyclonal Antibody
SKU:
CAB2749
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-599 of human IGF2BP2/IMP2 (NP_006539.3).
This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes.
Purification Method:
Affinity purification
Gene ID:
10644
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using IGF2BP2/IMP2 Rabbit pAb (CAB2749) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
