The IGF2BP2 Polyclonal Antibody (CAB1774) is a valuable tool for researchers studying IGF2BP2, a protein involved in mRNA metabolism and regulation of gene expression. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting.IGF2BP2, also known as insulin-like growth factor 2 mRNA-binding protein 2, plays a crucial role in post-transcriptional regulation of gene expression, particularly in the context of cell proliferation and differentiation.
Dysregulation of IGF2BP2 has been implicated in various diseases, including cancer and metabolic disorders, making it a promising target for therapeutic interventions.By detecting and analyzing IGF2BP2 expression, researchers can gain insights into its functional role in different cell types and pathological conditions. This antibody is ideal for studies in cell biology, molecular biology, and cancer research, providing a valuable tool for unraveling the complex mechanisms underlying disease development and progression.
Product Name:
IGF2BP2/IMP2 Rabbit Polyclonal Antibody
SKU:
CAB1774
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 330-599 of human IGF2BP2/IMP2 (NP_006539.3).
This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes.
Purification Method:
Affinity purification
Gene ID:
10644
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IGF2BP2/IMP2 Rabbit pAb (CAB1774) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
