The IGF2BP1 Polyclonal Antibody (CAB1517) is a valuable tool for researchers studying IGF2BP1, a protein involved in RNA binding and post-transcriptional regulation. This antibody, generated in rabbits, shows high specificity and reactivity with human samples, making it suitable for Western blot applications. By binding to IGF2BP1, this antibody allows for accurate detection and analysis of the protein in various cell types, making it ideal for studies in molecular biology and cancer research.IGF2BP1, also known as insulin-like growth factor 2 mRNA-binding protein 1, is known for its role in regulating mRNA stability and translation, impacting cellular processes such as cell growth and differentiation.
Dysregulation of IGF2BP1 has been linked to cancer development and progression, highlighting its potential as a therapeutic target in oncology research. By investigating the functions of IGF2BP1 using this antibody, researchers can gain insights into its role in disease pathogenesis and potentially identify novel treatment strategies.
Product Name:
IGF2BP1 Rabbit Polyclonal Antibody
SKU:
CAB1517
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 478-577 of human IGF2BP1/IMP1 (NP_006537.3).
This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10642
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using IGF2BP1/IMP1 Rabbit pAb (CAB1517) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
