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IGF2BP1/IMP1 Polyclonal Antibody (CAB22246)

SKU:
CAB22246
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €529
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:IGF2BP1/IMP1 Polyclonal Antibody
SKU:CAB22246
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human IMP1 (NP_006537.3).
Sequence:MNKL YIGN LNES VTPA DLEK VFAE HKIS YSGQ FLVK SGYA FVDC PDEH WAMK AIET FSGK VELQ GKRL EIEH SVPK KQRS RKIQ IRNI PPQL RWEV LDSL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1; P1
Positive Sample:HepG2,293F,NIH/3T3,Mouse brain,Rat kidney
Conjugate:Unconjugated
Cellular Localization:CRD-mediated mRNA stability complex, cytoplasm, cytoplasmic stress granule, cytosol, dendritic spine, growth cone, nucleoplasm, nucleus, P-body, perinuclear region of cytoplasm
Calculated MW:63kDa
Observed MW:64kDa

This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:10642
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts from normal (control) and knockdown (KD) HepG2 cells, using ZEB1 antibody (CAB22246) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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