The IGF2BP1/IMP1 Polyclonal Antibody is a valuable tool for researchers studying the IGF2BP1/IMP1 protein, which plays a key role in regulating mRNA stability, translation, and localization. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.IGF2BP1/IMP1 is a multifunctional protein involved in various cellular processes, including cell growth, differentiation, and tumorigenesis. Its overexpression has been linked to several types of cancer, making it an attractive target for cancer research.
By detecting and analyzing the IGF2BP1/IMP1 protein in different cell types, researchers can gain insights into its role in cancer progression and potentially develop targeted therapies.Further exploration of the IGF2BP1/IMP1 protein and its functions can provide valuable insights into its potential as a biomarker or therapeutic target in cancer and other diseases. This antibody is a valuable tool for researchers seeking to deepen their understanding of IGF2BP1/IMP1 and its implications in various biological processes.
Product Name:
IGF2BP1/IMP1 Polyclonal Antibody
SKU:
CAB22246
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human IMP1 (NP_006537.3).
CRD-mediated mRNA stability complex, cytoplasm, cytoplasmic stress granule, cytosol, dendritic spine, growth cone, nucleoplasm, nucleus, P-body, perinuclear region of cytoplasm
Calculated MW:
63kDa
Observed MW:
64kDa
This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10642
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts from normal (control) and knockdown (KD) HepG2 cells, using ZEB1 antibody (CAB22246) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
