The IGF2 Polyclonal Antibody (CAB14005) is a valuable tool for researchers studying Insulin-like growth factor 2 (IGF2), a key player in cellular growth and development. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the IGF2 protein, researchers can accurately detect and analyze its expression in various cell types, providing important insights into the role of IGF2 in physiology and disease.IGF2 is a crucial regulator of cell proliferation, differentiation, and survival, with implications in cancer, diabetes, and other metabolic disorders.
As a potent growth factor, IGF2 plays a significant role in tumorigenesis and metastasis, making it an attractive target for cancer research. By understanding the mechanisms underlying IGF2 activity, researchers can develop novel strategies for therapy and intervention in cancer and other related diseases.Overall, the IGF2 Polyclonal Antibody is a valuable resource for investigators exploring the complex functions of IGF2 in both normal physiology and disease states. Its high specificity and sensitivity make it an essential tool for advancing our understanding of IGF2 biology and its potential therapeutic applications.
Product Name:
IGF2 Rabbit Polyclonal Antibody
SKU:
CAB14005
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-127 of human IGF2 (NP_000603.1).
Sequence:
FYFS RPAS RVSR RSRG IVEE CCFR SCDL ALLE TYCA TPAK SERD VSTP PTVL PDNF PRYP VGKF FQYD TWKQ STQR LRRG LPAL LRAR RGHV LAKE LEAF RE
Tested Applications:
IF/ICCELISA
Recommended Dilution:
IF/ICC,1:50 - 1:200
Synonyms:
GRDF; SRS3; IGF-II; PP9974; C11orf43; IGF2
Conjugate:
Unconjugated
Cellular Localization:
Secreted.
Calculated MW:
20kDa
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3481
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using IGF2 Polyclonal Antibody (CAB14005) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
