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IGF2 Polyclonal Antibody

SKU:
CAB24842
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IF
€129 - €359
Frequently bought together:

Description

IGF2 Polyclonal Antibody (CAB24842)

The IGF2 Polyclonal Antibody is a valuable tool for research involving Insulin-like Growth Factor 2 (IGF2), a protein involved in cell growth, proliferation, and differentiation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.IGF2 is a key player in regulating cell processes such as cell survival and metabolism. Dysregulation of IGF2 expression has been implicated in various diseases, including cancer and developmental disorders. This antibody specifically targets the IGF2 protein, allowing for precise detection and analysis in different cell types.

Researchers studying cell signaling pathways, growth factors, and cancer biology will find this polyclonal antibody to be a valuable tool. By understanding the role of IGF2 in normal cellular functions and disease states, new therapeutic targets and treatment strategies may be identified. This antibody is essential for advancing research in fields such as oncology, developmental biology, and regenerative medicine.

Product Name:IGF2 Polyclonal Antibody
Product Code:CAB24842
Reactivity:Human, Mouse, Rat
Applications:Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat
Tested Applications:IF/ICC
Key Applications:Immunofluorescence
Recommended Dilution:IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Cellular Location:Secreted

This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 70-180 of human IGF2 (P01344).
Sequence:CCFRS CDLAL LETYC ATPAK SERDV STPPT VLPDN FPRYP VGKFF QYDTW KQSTQ RLRRG LPALL RARRG HVLAK ELEAF REAKR HRPLI ALPTQ DPAHG GAPPE MASNR K
Synonyms:IGF2, C11orf43, GRDF, IGF-II, PP9974, insulin like growth factor 2
Calculated MW:20kDa/26kDa
Observed MW:Refer to figures

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