IGF1R Rabbit Polyclonal Antibody (CAB12736)
- SKU:
- CAB12736
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | IGF1R Rabbit Polyclonal Antibody |
SKU: | CAB12736 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 741-910 of human IGF1R (NP_000866.1). |
Sequence: | DVMQ VANT TMSS RSRN TTAA DTYN ITDP EELE TEYP FFES RVDN KERT VISN LRPF TLYR IDIH SCNH EAEK LGCS ASNF VFAR TMPA EGAD DIPG PVTW EPRP ENSI FLKW PEPE NPNG LILM YEIK YGSQ VEDQ RECV SRQE YRKY GGAK LNRL NPGN YTAR IQAT SL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | IGFR; CD221; IGFIR; JTK13; IGF1R |
Positive Sample: | Mouse kidney,Mouse lung,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 155kDa |
Observed MW: | 100kDa |
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3480 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |