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IGF1 PAT6F8AT Monoclonal Antibody [PAT6F8AT] (CPAB0077)

SKU:
CPAB0077
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT6F8AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

IGF1 PAT6F8AT Monoclonal Antibody [PAT6F8AT] (CPAB0077)

The IGF1 Polyclonal Antibody (CPAB0077) is a valuable tool for researchers studying Insulin-like Growth Factor 1 (IGF1), a protein involved in cell growth, metabolism, and development. This antibody, raised in rabbits, is highly specific to human IGF1 and is validated for use in Western blot applications. It binds to the IGF1 protein, enabling accurate detection and analysis in a variety of cell types, making it ideal for studies in endocrinology, cancer research, and developmental biology.

IGF1 plays a critical role in promoting cell proliferation and survival, making it a key player in diseases like cancer, diabetes, and growth disorders. By understanding the activity of IGF1, researchers can uncover new insights into disease mechanisms and potentially develop targeted therapies. The IGF1 Polyclonal Antibody is a powerful tool for investigating the role of IGF1 in human health and disease.

Product Name:IGF1 PAT6F8AT Antibody
Product Sku:CPAB0077
Size:5μg
Host Species:Mouse
Immunogen:Anti-human IGF1 mAb, clone PAT6F8AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human IGF1 protein 49-118 amino acids purified from Ecoli.
Clone:PAT6F8AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:IGF1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin' (Daughaday et al., 1972). Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2; MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986; Rosenfeld, 2003).
Synonyms:Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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