The IFT81 Polyclonal Antibody (CAB4662) is a valuable tool for researchers studying the IFT81 protein, which is involved in intraflagellar transport (IFT) processes within cells. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the IFT81 protein, this antibody enables accurate detection and analysis in a variety of cell types.IFT proteins, such as IFT81, play an essential role in the formation and function of cilia, which are hair-like structures on the surface of cells that are involved in cell signaling and motility.
Dysregulation of IFT proteins can lead to various developmental disorders and diseases, making them important targets for research in fields such as cell biology and genetics. The IFT81 Polyclonal Antibody is a valuable tool for investigating the function and regulation of IFT81 in cellular processes, providing valuable insights for studies in ciliopathies and related conditions.
Product Name:
IFT81 Rabbit Polyclonal Antibody
SKU:
CAB4662
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 550-676 of human IFT81 (NP_054774.2).
The protein encoded by this gene, together with IFT74, forms a tubulin-binding module of intraflagellar transport complex B. This module is involved in transport of tubulin within the cilium, and the encoded protein is required for ciliogenesis. Mutations in this gene are a cause of short-rib polydactyly syndromes.
Purification Method:
Affinity purification
Gene ID:
28981
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IFT81 Rabbit pAb (CAB4662) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
