The IFT52 Polyclonal Antibody (PACO09887) offered by AssayGenie is a valuable tool for researchers studying the IFT52 protein, which is involved in intraflagellar transport. This antibody, produced in rabbits, has been validated for specificity in Western blot applications and is highly reactive with human samples.IFT52 is a key component of the intraflagellar transport system, which plays a critical role in the assembly and maintenance of cilia, specialized organelles involved in cell motility and signal transduction.
Dysregulation of ciliary function has been implicated in a range of human diseases, including ciliopathies and certain forms of cancer.By using the IFT52 Polyclonal Antibody, researchers can study the expression and function of IFT52 in various biological contexts, shedding light on the mechanisms underlying ciliary biology and its relevance to human health. This antibody is a valuable tool for investigators working in the fields of cell biology, developmental biology, and cancer research.
intraflagellar transport 52 homolog (Chlamydomonas);IFT52;C20orf9;CGI-53;NGD5;dJ1028D15.1 ;
UniProt Protein Function:
Involved in ciliogenesis as part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia (PubMed:27466190). Required for the anterograde transport of IFT88 (PubMed:27466190).
UniProt Protein Details:
NCBI Summary:
This gene encodes a conserved proline-rich protein that is a component of the intraflagellar transport-B (IFT-B) core complex. The encoded protein is essential for the integrity of the IFT-B core complex, and for biosynthesis and maintenance of cilia. Mutations in this gene are associated with ciliopathy that affects the skeleton. [provided by RefSeq, Oct 2016]
