The IFITM3 Polyclonal Antibody (PAC047074) is a vital tool for researchers studying the interferon-inducible transmembrane protein 46 (IFITM46), a key player in immune defense against viral infections. This antibody, derived from rabbit serum, is highly specific to human samples and is suitable for use in a variety of research applications, including Western blotting.IFITM46, also known as interferon-induced transmembrane protein 46, is a crucial component of the innate immune response, playing a pivotal role in restricting viral entry and replication within host cells.
Its function in viral immunity makes it a promising target for investigation in infectious disease research, particularly in understanding host-pathogen interactions and developing antiviral therapies.With its high specificity and sensitivity, the IFITM3 Polyclonal Antibody is an invaluable tool for scientists studying the mechanisms of viral infection and immune response modulation. By targeting IFITM46, researchers can gain insight into the molecular pathways that govern viral immunity and potentially identify novel strategies for combating infectious diseases.
Western blot. All lanes: IFT46 antibody at 8 µg/ml + Mouse skeletal muscle tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 35, 41 kDa. Observed band size: 35 kDa..
Immunohistochemistry of paraffin-embedded human melanoma using PACO47074 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human liver tissue using PACO47074 at dilution of 1:100.
Background:
Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity).
Synonyms:
Intraflagellar transport protein 46 homolog, IFT46, C11orf2 C11orf60
UniProt Protein Function:
IFT46: Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis. Belongs to the IFT46 family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 11q23.3Cellular Component: centrosome; cytoplasm; motile primary cilium; ciliumMolecular Function: protein C-terminus bindingBiological Process: smoothened signaling pathway; protein stabilization; organelle organization and biogenesis; intraflagellar transport; cilium biogenesis
