The IFNL4 Antibody (PAC047838) is a polyclonal antibody designed for research involving IFNL4, a protein involved in immune regulation and antiviral responses. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.IFNL4, also known as interferon lambda 4, is a member of the interferon lambda family that plays a critical role in host defense against viral infections. It is involved in the regulation of immune responses and has been implicated in the pathogenesis of various viral diseases. Studies have shown that IFNL4 expression is induced in response to viral infections, highlighting its importance in antiviral immunity.
The IFNL4 Antibody (PAC047838) binds specifically to the IFNL4 protein, allowing for accurate detection and analysis in a variety of cell types. This antibody is a valuable tool for researchers studying immunology, virology, and infectious diseases, as it provides insight into the role of IFNL4 in immune response modulation and antiviral defense mechanisms. Understanding the function of IFNL4 is essential for the development of novel therapeutic strategies targeting viral infections and immune-related disorders.
Antibody Name:
IFNL4 Antibody (PACO47838)
Antibody SKU:
PACO47838
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Interferon lambda-4 protein (34-76AA)
Immunofluorescent analysis of Hela cells using PACO47838 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Cytokine that may trigger an antiviral response activating the JAK-STAT pathway and up-regulating specifically some interferon-stimulated genes.
Synonyms:
Interferon lambda-4 (IFN-lambda-4), IFNL4
UniProt Protein Function:
IFNL4: Cytokine that may trigger an antiviral response activating the JAK-STAT pathway and up-regulating specifically some interferon-stimulated genes. Belongs to the lambda interferon family. Up-regulated by polyinosinic:polycytidylic acid (polyI:C) which mimics double-stranded hepatitis C virus. 4 isoforms of the human protein are produced by alternative splicingChromosomal Location of Human Ortholog: 19q13.2Cellular Component: cytoplasm; extracellular spaceMolecular Function: cytokine activityBiological Process: defense response to virus; innate immune response; regulation of T cell activation; tyrosine phosphorylation of Stat1 protein; tyrosine phosphorylation of Stat2 protein
