The IFNGR2 Polyclonal Antibody (CAB14221) is a valuable tool for researchers studying the IFNGR2 protein, a key component of the interferon gamma receptor complex. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the IFNGR2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it well-suited for investigations in immunology and cancer research.IFNGR2 plays a crucial role in mediating the effects of interferon gamma, a potent immune regulator involved in antiviral defense, anti-tumor immunity, and autoimmune responses.
Understanding the function of IFNGR2 is essential for unraveling the complex mechanisms governing immune signaling and identifying potential therapeutic targets for diseases such as cancer, infectious diseases, and autoimmune disorders. The IFNGR2 Polyclonal Antibody provides researchers with a reliable tool to investigate the role of IFNGR2 in immune regulation and disease pathogenesis.
Product Name:
IFNGR2 Rabbit Polyclonal Antibody
SKU:
CAB14221
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 221-322 of human IFNGR2 (NP_005525.2).
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
Purification Method:
Affinity purification
Gene ID:
3460
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IFNGR2 Rabbit pAb (CAB14221) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
