The IFNGR1 Polyclonal Antibody (CAB5748) is a valuable tool for researchers studying the interferon gamma receptor 1 (IFNGR1) protein, which plays a key role in the immune response to infections and cancer. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting IFNGR1 in human samples, making it an ideal choice for Western blot applications.IFNGR1 is a crucial component of the interferon gamma signaling pathway, which is essential for the immune system's ability to fight off pathogens and tumor cells. Dysregulation of this pathway has been linked to various diseases, including autoimmune disorders and certain types of cancer.
By utilizing the IFNGR1 Polyclonal Antibody, researchers can investigate the expression and function of IFNGR1 in different cell types, paving the way for a better understanding of immune responses and the development of potential therapeutic interventions.Overall, the IFNGR1 Polyclonal Antibody is a valuable tool for immunology and cancer research, enabling scientists to delve deeper into the molecular mechanisms underlying immune system function and disease pathogenesis. Its versatility and reliability make it a valuable asset for studies aimed at uncovering novel therapeutic targets and strategies for enhancing immune responses.
Product Name:
IFNGR1 Rabbit Polyclonal Antibody
SKU:
CAB5748
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 270-489 of human IFNGR1 (NP_000407.1).
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
Purification Method:
Affinity purification
Gene ID:
3459
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IFNGR1 Rabbit pAb (CAB5748) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
